MED6-189

MED6-189, a kalihinol analog, disrupts apicoplast function and vesicular trafficking in P. falciparum malaria (IC50 < 50 nM). MED6-189 targets the apicoplast, a nonphotosynthetic plastid found in most Apicomplexa parasites that is crucial for the synthesis of isoprenoids.


Cat. No.: EX-A12809	Purity: >98%

	Chemical structure of MED6-189

For research only, Do not use for Human!

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CAS No.	2650073-66-6
Purity	>98%
Formula	C17H26N2O
Mol Weight	274.4011
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Z. CHAHINE, et al. A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria. Science. 2024 Sep 27;385(6716):eadm7966.
CoA	CoA of MED6-189

Smiles:	[H][C@]12CC[C@@](C#N)([C@@H]([C@@]1([C@H](CC[C@@]2(C#N)C)C(C)C)[H])O)C


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