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Product Information:

MDM2-IN-1

MDM2 ligand 5 is a Ligand for E3 Ligase that can be used for the synthesis of PROTACs .

Cat. No.: EX-A10262    Purity: >98%
Chemical
Chemical structure of MDM2-IN-1


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg841in_stock
100mg1440in_stock
250mg2701in_stock
500mg4706in_stock


CAS No.1410737-09-5
Purity>98%
FormulaC23H21Cl2FN2O3
Mol Weight463.329
ColorWhite to yellow
StateSolid
SolubilitySoluble in DMSO/DMF
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Acharyya RK, et al. MD-4251: A First-in-Class Oral MDM2 Degrader Inducing Complete Tumor Regression with Single-Dose Administration. J Med Chem. 2025 Jul 10;68(13):13249-13267.

CoACoA of MDM2-IN-1
Smiles:O=C([C@H](N1)[C@H](C2=CC=CC(Cl)=C2F)[C@]3(C(NC4=C3C=CC(Cl)=C4)=O)C51CCCCC5)O

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