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Product Information:

MCU-i4

MCU i4 is a negative modulator of mitochondrial calcium (Ca2+) uniporter (MCU) complex. MCU i4 reduces mitochondrial Ca2+ uptake and impairs muscle cell growth.

Cat. No.: EX-A5005    Purity: >98%
Chemical
Chemical structure of MCU-i4


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg785In-stock
1g1100In-stock
5gget quoteIn-stock
10gget quoteIn-stock


SynonymsMCU i4
Synonyms 2MCUi4
CAS No.371924-24-2
Purity>98%
FormulaC23H27N3O2
Mol Weight377.4794
ColorLight yellow to yellow
Statesolid powder
SolubilitySoluble in DMSO 12.5 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Giulia Di Marco, et al. A High-Throughput Screening Identifies MICU1 Targeting Compounds. Cell Rep. 2020 Feb 18;30(7):2321-2331.e6.

[2]. Alessandro Rimessi, et al. Update on Calcium Signaling in Cystic Fibrosis Lung Disease. Front Pharmacol. 2021 Mar 11;12:581645.

CoACoA of MCU-i4
Smiles:CCN(CC)C1=CC=C(C=C1)NC2=C3C=C(C=CC3=NC=C2C(=O)OCC)C

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