Mc-Phe-Lys(Boc)-PAB

ZYN57939 is RNA polymerase I inhibitor for treating RNA polymerase I- mediated diseases. ZYN57939 showed inhibitory activity with IC50 of 0.855 μM against human HT- 29 cancer cell lines.


Cat. No.: EX-A5033	Purity: >98%

	Chemical structure of Mc-Phe-Lys(Boc)-PAB

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	885	In-stock
250mg	1350	In-stock
1g	2500	In-stock

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CAS No.	756487-18-0
Purity	>98%
Formula	C37H49N5O8
Mol Weight	691.8137
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 2 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Li MZ, Meng T, Song SS, Bao XB, Ma LP, Zhang N, Yu T, Zhang YL, Xiong B, Shen JK, Miao ZH, He JX. Discovery of MTR-106 as a highly potent G-quadruplex stabilizer for treating BRCA-deficient cancers. Invest New Drugs. 2021 Oct;39(5):1213-1221.
CoA	CoA of Mc-Phe-Lys(Boc)-PAB

Smiles:	O=C([C@@H](NC([C@@H](NC(CCCCCN1C(C=CC1=O)=O)=O)CC2=CC=CC=C2)=O)CCCCNC(OC(C)(C)C)=O)NC3=CC=C(C=C3)CO


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