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Product Information:

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is a agent-linker conjugate for ADC, contains the ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and a DNA topoisomerase I inhibitor Exatecan. MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan synthesized ADC can be used in study of cancer.

Cat. No.: EX-A9093    Purity: >98%
Chemical
Chemical structure of MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg693in_stock
100mg1029in_stock
250mg1796in_stock
500mg3043in_stock
1g5067in_stock


CAS No.2414393-22-7
Purity>98%
FormulaC55H60FN9O13
Mol Weight1074.1158
ColorOff-white to light yellow
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20°C, sealed storage, away from moisture and light; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. HUA Haiqing, et al. Antibody-drug conjugate and medical use thereof. Patent WO2021190564A1.

CoACoA of MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
Smiles:O=C(C1(CCC1)OCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95

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