MC-GGFG-PAB-Exatecan

MC-GGFG-PAB-Exatecan is a linker-drug conjugate, consisting of the MC-GGFG-PAB linker and the Topoisomerase I inhibitor Exatecan. MC-GGFG-PAB-Exatecan can be used to synthesize antibody-drug conjugates (ADCs). MC-GGFG-PAB-Exatecan applies to cancer research.


Cat. No.: EX-A13245	Purity: >98%

	Chemical structure of MC-GGFG-PAB-Exatecan

For research only, Do not use for Human!

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CAS No.	2928560-25-0
Purity	>98%
Formula	C57H58FN9O13
Mol Weight	1096.1213
Color	Light yellow to yellow
State	Solid
Solubility	DMSO : ? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture and light; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Lei Shi, et al. Conjugates, compositions and methods of use. Patent. WO2023131219 A1. WIPO (PCT). 2023-01-05.
CoA	CoA of MC-GGFG-PAB-Exatecan

Smiles:	N(C(OCC1=CC=C(NC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(CCCCCN3C(=O)C=CC3=O)=O)=O)=O)=O)=O)C=C1)=O)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9


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