MC-betaglucuronide-MMAE-1

MC-betaglucuronide-MMAE-1 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.


Cat. No.: EX-A11836	Purity: >98%

	Chemical structure of MC-betaglucuronide-MMAE-1

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	1800	In-stock
25mg	4000	In-stock
50mg	get quote	In-stock
100mg	get quote	In-stock
250mg	get quote	Inquire
500mg	get quote	Inquire

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CAS No.	1703778-92-0
Purity	>98%
Formula	C66H98N8O20
Mol Weight	1323.5259
Color	White to off-white
State	Solid
Solubility	DMSO : ? 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, protect from light; The compound is unstable in solutions, freshly prepared is recommended.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinical Cancer Research (2010), 16(3), 888-897.
CoA	CoA of MC-betaglucuronide-MMAE-1

Smiles:	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC(=C(C=C3)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)NC(=O)CCNC(=O)CCCCCN5C(=O)C=CC5=O


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