MBP Ac1-9 (4Y)

MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis .


Cat. No.: EX-A17312	Purity: >98%

	Chemical structure of MBP Ac1-9 (4Y)

For research only, Do not use for Human!

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CAS No.	167278-49-1
Purity	>98%
Formula	C47H75N17O16
Mol Weight	1134.2028
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Huang J C, et al. T cell recognition of distinct peptide: I-Au conformers in murine experimental autoimmune encephalomyelitis[J]. The Journal of Immunology, 2003, 171(5): 2467-2477.
CoA	CoA of MBP Ac1-9 (4Y)

Smiles:	C([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@@H](NC(C)=O)C)=O)CO)=O)CCC(N)=O)=O)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(N)=O)=O)CO)=O)CCC2


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