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Product Information:

MAX-10181

MAX-10181 (PD-1/PD-L1-IN-30) is a PD-1/PD-L1 binding inhibitor, with an IC50 value of 0.018 μM. MAX-10181 can be used for research of cancers and other related diseases.

Cat. No.: EX-A8085    Purity: >98%
Chemical
Chemical structure of MAX-10181


For research only, Do not use for Human!

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CAS No.2171558-14-6
Purity>98%
FormulaC29H28F3NO5
Mol Weight527.5315
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent    -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wang, Yuguang, et al. Aromatic acetylene or aromatic ethylene compound, intermediate, preparation method, pharmaceutical composition and use thereof. Patent. WO2018006795.

CoACoA of MAX-10181
Smiles:CC1=C(C=CC=C1/C=C/C2=C(C=CC(CNC(CO)(C)C(O)=O)=C2)C(F)(F)F)C3=CC=C(OCCO4)C4=C3

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