MAT-POS-e194df51-1

MAT-POS-e194df51-1 is an orally active, non-covalent and non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 value of 37nM. MAT-POS-e194df51-1 is cytotoxic with EC50 values of 64 nM and 126 nM in A549-ACE2-TMPRSS2 cells and HeLa -ACE2 cells, respectively.


Cat. No.: EX-A17064	Purity: >98%

	Chemical structure of MAT-POS-e194df51-1

For research only, Do not use for Human!

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CAS No.	2765433-05-2
Purity	>98%
Formula	C24H21ClN4O3S
Mol Weight	480.967
Color	White to off-white
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C 3 years, 4°C 2 years; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Boby ML, et al. Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science. 2023 Nov 10;382(6671):eabo7201.
CoA	CoA of MAT-POS-e194df51-1

Smiles:	N#CC1(CC1)CS(=O)(N2CC3=C([C@@H](C2)C(NC4=C5C=CC=CC5=CN=C4)=O)C=C(C=C3)Cl)=O


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