Maralixibat chloride

Maralixibat (SHP625) chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. Maralixibat chloride can be used for the research of rare cholestatic liver diseases including Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC) and biliary atresia .


Cat. No.: EX-A7812	Purity: >98%

	Chemical structure of Maralixibat chloride

For research only, Do not use for Human!

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Synonyms	SHP625 chloride
Synonyms 2	LUM001 chloride
CAS No.	228113-66-4
Purity	>98%
Formula	C40H56ClN3O4S
Mol Weight	710.408
Color	White to light yellow
State	solid powder
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	4°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Shirley M. Maralixibat: First Approval [published correction appears in Drugs. 2021 Dec 6;:]. Drugs. 2022;82(1):71-76. [2].Mayo MJ, et al. A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. Hepatol Commun. 2019 Feb 1;3(3):365-381.
CoA	CoA of Maralixibat chloride

Smiles:	O=S1(CC(CCCC)(CCCC)[C@H](O)[C@H](C2=CC=C(OCC3=CC=C(C[N+]4(CC5)CCN5CC4)C=C3)C=C2)C6=CC(N(C)C)=CC=C61)=O.[Cl-]


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