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Product Information:

MAPPGMRLRSGRSTGAPLTRGSC

LANA is a KSHV latency-associated nuclear antigen. The core function of LANA is to act as an "anchor" for the viral genome, attaching it to the chromatin of the host cell. LANA ensures that the episomal DNA of KSHV replicates together with the host chromosome and is evenly distributed among the daughter cells, thereby maintaining the latent infection of the virus in the cell population. LANA can regulate the transcription of viral and host cell genes, and regulate certain host cell genes to promote cell survival. LANA can be used to study the viral DNA tethering structure .

Cat. No.: EX-A17241    Purity: >98%
Chemical
Chemical structure of MAPPGMRLRSGRSTGAPLTRGSC


For research only, Do not use for Human!

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CAS No.878495-58-0
Purity>98%
FormulaC95H167N35O29S3
Mol Weight2359.755
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Schneider WM, et al. Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag. Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):9487-92.

CoACoA of MAPPGMRLRSGRSTGAPLTRGSC
Smiles:C(=O)([C@H]1N(C([C@@H](NC([C@H](CCSC)N)=O)C)=O)CCC1)N2[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(=O)N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(O)=O)CS)=O)CO)=O)=O)CCCNC(=N)N)=O)[C@@

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