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Product Information:

MAO-B-IN-39

MAO-B-IN-39 (compound11) is a selective monoamine oxidase B (MAO-B) inhibitor. MAO-B-IN-39 inhibits MAO-Bwith an IC50 of 3.61 μM. MAO-B-IN-39 demonstrates a potent NRF2 induction capacity. MAO-B-IN-39 exhibits potent anti-inflammatory and neuroprotective activity in OS (oxidative stress)-related in vitro models. MAO-B-IN-39 demonstrates high liver microsomal stability and favorable pharmacokinetics in mice. MAO-B-IN-39 is potential for Parkinson’s disease (PD) research .

Cat. No.: EX-A15793    Purity: >98%
Chemical
Chemical structure of MAO-B-IN-39


For research only, Do not use for Human!

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CAS No.3094045-97-0
Purity>98%
FormulaC17H13FN2O
Mol Weight280.2963
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zhang C, et al. Design, Synthesis, and Biological Evaluation of Chiral-Proline Derivatives as Novel HSP90 Inhibitors. ACS Med Chem Lett. 2025 Jan 22;16(2):301-310.

[2]. Duarte P, et al. Network-Based Drug Optimization toward the Treatment of Parkinson's Disease: NRF2, MAO-B, Oxidative Stress, and Chronic Neuroinflammation. J Med Chem. 2025 Feb 13;68(3):3495-3517.

CoACoA of MAO-B-IN-39
Smiles:O=C(NC1=CC=C2NC=CC2=C1)/C=C/C3=C(C=CC=C3)F

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