malonyl-NAC

malonyl-NAC increases cellular propylation, resulting in reduced endogenous GAPDH activity. malonyl-NAC increases GAPDH malonylation in cells and inhibits pyruvate kinase activity. In addition, malonyl-NAC limits the metabolism and proliferation of a highly glycolytic kidney cancer cell line harboring a tricarboxylic acid cycle mutation .


Cat. No.: EX-A9712	Purity: >98%

	Chemical structure of malonyl-NAC

For research only, Do not use for Human!

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CAS No.	2361327-06-0
Purity	>98%
Formula	C9H15NO4S
Mol Weight	233.285
Color	Colorless to light yellow
State	Oil
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kulkarni RA, et al. Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling. Cell Chem Biol. 2017 Feb 16;24(2):231-242.
CoA	CoA of malonyl-NAC

Smiles:	O=C(OCC)CC(=O)SCCNC(=O)C


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