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Product Information:

M-1211

M‑1121 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression.

Cat. No.: EX-A8230    Purity: >98%
Chemical
Chemical structure of M-1211


For research only, Do not use for Human!

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CAS No.2377337-93-2
Purity>98%
FormulaC42H57FN6O6S
Mol Weight793.002
ColorWhite to yellow
Statesolid powder
SolubilityDMSO : 7.69 mg/mL 
Shelf Life>2 years if stored properly
StoragePowder , sealed storage, away from moisture and light, -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Zhang M, et al. Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression. J Med Chem. 2021;64(14):10333-10349.

CoACoA of M-1211
Smiles:COC(N[C@@H](CCC1)[C@@]1([H])[C@](C2CCN(CC2)CC3(CN(C4=CC=C(C=C4)S(=O)(N5[C@@]6([H])C[C@@](N(C6)C(C=C)=O)([H])C5)=O)C3)OC)(C7=CC(F)=CC=C7)CN8CCC8)=O

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