LYP-IN-1

LYP-IN-1 is a potent, selective and specific LYP inhibitor with a Ki and an IC50 of 110 nM and 0.259 μM, respectively. LYP-IN-1 also has selectivity for a large panel of PTPs, such as SHP1 (IC50=5 μM) and SHP2 (IC50=2.5 μM).


Cat. No.: EX-A8169	Purity: >98%

	Chemical structure of LYP-IN-1

For research only, Do not use for Human!

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CAS No.	1404436-51-6
Purity	>98%
Formula	C28H20ClNO6
Mol Weight	501.915
Color	Off-white to light yellow
State	solid powder
Solubility	DMSO : 2 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. A Potent and Selective Small-Molecule Inhibitor for the Lymphoid-Specific Tyrosine Phosphatase (LYP), a Target Associated With Autoimmune Diseases
CoA	CoA of LYP-IN-1

Smiles:	O=C(C1=C(O)C=C(OC(C2=CC=C(OCC(NC3CC3)=O)C=C2)=C4C#CC5=CC=CC(Cl)=C5)C4=C1)O


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