LYG-202

LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities. It inhibits proliferation of HepG2, MCF-7, HeLa, BGC-823, MDA-MB-435, and HCT116 cancer cells in vitro (IC50s = 4.74-27.70 μM) via induction of apoptosis and dissipation of the mitochondrial membrane potential. LYG-202 reduces tumor growth in S180 sarcoma cell-inoculated mice.


Cat. No.: EX-A7654	Purity: >98%

	Chemical structure of LYG-202

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	450	Inquire
50mg	750	Inquire
100mg	1250	Inquire
200mg	1850	Inquire

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CAS No.	1175077-25-4
Purity	>98%
Formula	C25H30N2O5
Mol Weight	438.5161
Color	Light yellow to yellow
State	solid powder
Solubility	DMSO : 5 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zeng, Shi et al. “LYG-202, a new flavonoid with a piperazine substitution, shows antitumor effects in vivo and in vitro.” Biochemical and biophysical research communications vol. 385,4 (2009): 551-6. [2]. Chen, Yan et al. “LYG-202, a newly synthesized flavonoid, exhibits potent anti-angiogenic activity in vitro and in vivo.” Journal of pharmacological sciences vol. 112,1 (2010): 37-45.
CoA	CoA of LYG-202


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