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Product Information:

LY2880070

LY2880070 is an orally active CHK1 inhibitor exhibited IC50 value of < 0.001 μM. LY2880070 can be used for cancer research

Cat. No.: EX-A3339    Purity: >98%
Chemical
Chemical structure of LY2880070


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg500In-stock
100mg750In-stock
250mg1250In-stock
500mg1950In-stock
1g2750In-stock
5g6870In-stock


SynonymsLY-2880070
CAS No.1375637-35-6
Purity>98%
FormulaC19H23N7O2
Mol Weight381.4316
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Quincy S, et al. A phase Ib study of oral Chk1 inhibitor LY2880070 in combination with gemcitabine in patients with advanced or metastatic cancer. Journal of Clinical Oncology 2020 38:15_suppl, 3581.

[2]. Kailong Jiang, et al. Functions and inhibitors of CHK1 in cancer therapy. Medicine in Drug Discovery. Volume 22, June 2024, 100185.

[3]. WO2012064548 A1

CoACoA of LY2880070
Smiles:CC1=CC=C(C2=NNC(NC3=NC(O[C@H]4CNCCC4)=CN=C3)=C2)C(OC)=N1

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