LY 344864

LY 344864 is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent.


Cat. No.: EX-A417	Purity: >98%

	Chemical structure of LY 344864

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	1185	In-stock
500mg	1785	In-stock
1g	2385	In-stock

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Synonyms	LY344864
Synonyms 2	LY-344864
CAS No.	186544-26-3
Purity	>98%
Formula	C21H23ClFN3O
Mol Weight	387.878
Color	white to off-white
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Phebus LA, Johnson KW, Zgombick JM, Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brainpenetration and activity in the neurogenic dural inflammation model of migraine. Life Sci. 1997;61(21):2117-26. [2]. Scholpa NE, et al. 5-HT1F receptor-mediated mitochondrial biogenesis for the treatment of Parkinson's disease. Br J Pharmacol. 2018 Jan;175(2):348-358.
CoA	CoA of LY 344864

Smiles:	Cl.CN(C)[C@@H]1CCC2=C(C1)C1=C(N2)C=CC(NC(=O)C2=CC=C(F)C=C2)=C1


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