LY-295427

LY 295427 is a LDL receptor modulator and a hypocholesterolemic agent. LY 295427 derepresses the transcription of the LDLR (LDL Receptor). LY 295427 can be used for hypercholesterolemia research.


Cat. No.: EX-A13895	Purity: >98%

	Chemical structure of LY-295427

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	498	In-stock
50mg	798	In-stock
100mg	1200	In-stock

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Synonyms	Agisterol
CAS No.	152755-31-2
Purity	>98%
Formula	C30H52O
Mol Weight	428.7333
Color	White to off-white
State	Solid
Solubility	Methanol : 15.91 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years, 4°C, 2 years; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bowling N, et al. LY295427, a novel hypocholesterolemic agent, enhances [3H]25-hydroxycholesterol binding to liver cytosolic proteins. J Lipid Res. 1996 Dec;37(12):2586-98. [2]. George Chang, et al. Low density lipoprotein receptor up-regulation. Expert Opinion on Therapeutic Patents. Volume 9, 1999-Issue 5. [3]. Bensch WR, et al. Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters. J Pharmacol Exp Ther. 1999 Apr;289(1):85-92.
CoA	CoA of LY-295427

Smiles:	CC(CCC[C@H]([C@H]1CC[C@]2([C@@]3(CC[C@]4([C@@H]([C@@H](CC[C@@]4([C@]3(CC[C@]12C)[H])C)O)CC=C)[H])[H])[H])C)C


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