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Product Information:

Lupiwighteone

Lupiwighteone is an isoflavone present widely in wild-growing plants, with antioxidant, antimicrobial and anticancer effects. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway .

Cat. No.: EX-A15620    Purity: >98%
Chemical
Chemical structure of Lupiwighteone


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5g1000in-stock


Synonyms8-prenylgenistein
CAS No.104691-86-3
Purity>98%
FormulaC20H18O5
Mol Weight338.3539
ColorOff-white to light yellow
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, protect from light, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Won YS, et al. Lupiwighteone induces caspase-dependent and -independent apoptosis on human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway. Food Chem Toxicol. 2020 Jan;135:110863.

[2]. Ren J, et al. Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells. Anticancer Drugs. 2015 Jul;26(6):599-611.

[3]. Li XL, Sui L, Lin FH, Lian Y, Ai LZ, Zhang Y. Differential effects of genistein and 8-prenylgenistein on reproductive tissues in immature female mice. Pharm Biol. 2019;57(1):226-230.

CoACoA of Lupiwighteone
Smiles:O=C1C2=C(O)C=C(O)C(C/C=C(C)\C)=C2OC=C1C3=CC=C(O)C=C3

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