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Product Information:

LUNA18

LUNA18 is an orally active KRAS inhibitor with an IC50 of ＜2 nM against KRASG12D-SOS. LUNA18 can be used for the research of cancer.

Cat. No.: EX-A8086    Purity: >98%
Chemical
Chemical structure of LUNA18


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg1900In-stock
100mg2800In-stock
250mg3900In-stock
500mgget quoteIn-stock
1g9800In-stock


SynonymsPaluratide
CAS No.2676177-63-0
Purity>98%
FormulaC73H105F5N12O12
Mol Weight1437.68
Colorwhite to off-white
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>1 years if stored properly
StoragePowder    -20°C, 1 year 
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Tanada M, et al. Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J Am Chem Soc. 2023 Aug 2;145(30):16610-16620.

CoACoA of LUNA18
Smiles:CC1=CC=C(C[C@@H](C(N(CC(N[C@H](C(N2CCC[C@H]2C(NC3(CCCC3)C(N(C)[C@H](C(N4C)=O)C5CCCC5)=O)=O)=O)CCC6=CC(F)=C(C(F)=C6)C(F)(F)F)=O)C)=O)N(C([C@@H]7CCN7C([C@H](C)N(C)C([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)N(C)C(C[C@H]4C(N(C)C)=O)=O)=O)=O)=O)=O)CC)C=C1

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