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Product Information:

Lu AF27139

Lu AF27139 is a novel rodent-active and CNS-penetrant P2X7 receptor antagonist.

Cat. No.: EX-A5507    Purity: >97%
Chemical
Chemical structure of Lu AF27139


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg650In-stock
100mg950In-stock
250mg1550In-stock
500mg2150In-stock
1g3900In-stock
5g9600Inquire


CAS No.2097117-06-9
Purity>97%
FormulaC21H19ClF3N5O2S
Mol Weight497.921
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO 125 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Hopper AT, Juhl M, Hornberg J, Badolo L, Kilburn JP, Thougaard A, Smagin G, Song D, Calice L, Menon V, Dale E, Zhang H, Cajina M, Nattini ME, Gandhi A, Grenon M, Jones K, Khayrullina T, Chandrasena G, Thomsen C, Zorn SH, Brodbeck R, Poda SB, Staal R, Möller T. Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139. J Med Chem. 2021 Apr 22;64(8):4891-4902. doi: 10.1021/acs.jmedchem.0c02249. Epub 2021 Apr 6. PMID: 33822617.
CoACoA of Lu AF27139

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