LSD1/HDAC-IN-1

LSD1/HDAC-IN-1 (compound 2) is a potent inhibitor of HDAC and LSD1, with IC50s of 0.125 nM, 0.373 nM, 0.0118 nM, 0.103 nM, and 0.571 μM for HDAC1, HDAC2, HDAC6, HDAC8 and LSD1, respectively. LSD1/HDAC-IN-1 plays an important role in cancer research.


Cat. No.: EX-A11668	Purity: >98%

	Chemical structure of LSD1/HDAC-IN-1

For research only, Do not use for Human!

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CAS No.	3056145-98-0
Purity	>98%
Formula	C18H18N2O4S
Mol Weight	358.412
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Po-Yu Chou, et al. Syntheses of LSD1/HDAC Inhibitors with Demonstrated Efficacy against Colorectal Cancer: In Vitro and In Vivo Studies Including Patient-Derived Organoids. J Med Chem. 2024 Oct 10;67(19):17207-17225.
CoA	CoA of LSD1/HDAC-IN-1

Smiles:	N(S(=O)(=O)C1=CC(/C=C/C(NO)=O)=CC=C1)[C@H]2[C@@H](C2)C3=CC=CC=C3


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