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Product Information:

LP99

LP99, an epigenetic probe, is a potent and selective inhibitor of the BRD7 and BRD9 bromodomains with a Kd of 99 nM against BRD9. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells.

Cat. No.: EX-A4757    Purity: >98%
Chemical
Chemical structure of LP99


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg500In-stock
50mgget quoteIn-stock
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CAS No.1808951-93-0
Purity>98%
FormulaC26H30ClN3O4S
Mol Weight516.052
ColorWhite to light yellow
StateSolid
SolubilityDMSO : 50 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Clark PG, et al. LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor. Angew Chem Int Ed Engl. 2015 May 18;54(21):6217-21.

CoACoA of LP99
Smiles:CC1=CC(=O)N(C2=C1C=CC(=C2)N3[C@@H]([C@H](CCC3=O)NS(=O)(=O)CC(C)C)C4=CC=C(C=C4)Cl)C

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