LP-65

LP-65 is a dual inhibitor of MEK (IC50=83.2 nM) and mTOR (IC50=40.5 nM). LP-65 blocks MEK and mTOR signaling pathways and inhibits tumor cell proliferation and migration. LP-65 is promising for research of cancers.


Cat. No.: EX-A13275	Purity: >98%

	Chemical structure of LP-65

For research only, Do not use for Human!

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Purity	>98%
Formula	C47H53F3IN7O10
Mol Weight	1059.8643
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Van Dort ME, et al. Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents. J Med Chem. 2025 Jun 12;68(11):11406-11418.
CoA	CoA of LP-65

Smiles:	FC1=C(F)C(NC2=C(F)C=C(I)C=C2)=C(C(NOCCOCCOCCOCCC(OCC3=CC(C4=CC=C(C(N5CCOC[C@@H]5C)=NC(N6CCOC[C@@H]6C)=N7)C7=N4)=CC=C3OC)=O)=O)C=C1


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