Lovastatin acid

Lovastatin acid (Mevinolinic acid; MSD803), an active metabolite of Lovastatin, is a potent competitive HMG-CoA reductase inhibitor with a Ki of 0.6 nM. Lovastatin acid acts as a competitive inhibitor with respect to substrate HMG-CoA, interfering cholesterol synthesis. Lovastatin acid can be used for the research of hypercholesterolemia .


Cat. No.: EX-A10840	Purity: >98%

	Chemical structure of Lovastatin acid

For research only, Do not use for Human!

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Synonyms	Mevinolinic acid
Synonyms 2	MSD803
CAS No.	75225-51-3
Purity	>98%
Formula	C24H38O6
Mol Weight	422.5549
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Alberts AW, et al. Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent. Proc Natl Acad Sci U S A. 1980;77(7):3957-3961.
CoA	CoA of Lovastatin acid

Smiles:	O=C(C[C@@H](C[C@@H](CC[C@H]1[C@H](C=CC2=C[C@@H](C[C@@H]([C@]12[H])OC([C@H](CC)C)=O)C)C)O)O)O


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