Loreclezole hydrochloride

Loreclezole hydrochloride, an antiepileptic compound, is a selective GABAA receptor modulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors.


Cat. No.: EX-A11113	Purity: >98%

	Chemical structure of Loreclezole hydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
100mg	948	In-stock
1g	2480	In-stock

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Synonyms	R 72063 hydrochloride
CAS No.	2227372-56-5
Purity	>98%
Formula	C10H7Cl4N3
Mol Weight	310.995
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Wingrove PB, et al. The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4569-73. [2]. Sanna E, et al. Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit. Neuropharmacology. 1996;35(12):1753-60. [3]. Green AR, et al. A behavioural and neurochemical study in rats of the pharmacology of loreclezole, a novel allosteric modulator of the GABAA receptor. Neuropharmacology. 1996;35(9-10):1243-50.
CoA	CoA of Loreclezole hydrochloride

Smiles:	ClC1=CC=C(/C(Cl)=C/N2N=CN=C2)C(Cl)=C1.[H]Cl


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