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Product Information:

LMI070

Branaplam (LMI070) is a highly selective, small-molecule splicing modulators of survival motor neuron‑2 (SMN2) with an EC50 of 0.02 μM.

Cat. No.: EX-A5962    Purity: >98%
Chemical
Chemical structure of LMI070


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg765In-stock
200mg1065In-stock
500mg1565In-stock
1g2265In-stock
5g5600In-stock


SynonymsBranaplam
Synonyms 2NVS-SM1
CAS No.1562338-42-4
Purity>98%
FormulaC22H27N5O2
Mol Weight393.4821
Color White to yellow
Statesolid powder
SolubilityDMSO : 31.25 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. heung, Atwood K et al. Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA). Journal of medicinal chemistry vol. 61,24 (2018): 11021-11036.

CoACoA of LMI070

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