LLC0424

LLC0424 is a potent and selective cereblon-based PROTAC nuclear receptor-binding SET domain-containing 2 (NSD2) degrader. LLC0424 effectively degraded NSD2 with a DC50 of 20 nM in RPMI-8402 cells. LLC0424 selectively induces NSD2 degradation in a cereblon- and proteasome-dependent fashion.


Cat. No.: EX-A17562	Purity:

	Chemical structure of LLC0424

For research only, Do not use for Human!

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Synonyms	LLC0424 PROTAC
CAS No.	3061315-33-8
Formula	C45H41N7O9
Mol Weight	823.8485

CoA	CoA of LLC0424

Smiles:	O=C(N1)COC2=C1C=CC(C(N(C3CC3)CC4=CC=C(C(NC5=CC=C(C(NC6CCN(C7=CC8=C(C(N(C(C(N9)=O)CCC9=O)C8=O)=O)C=C7)CC6)=O)C=C5)=O)C=C4)=O)=C2


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