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Product Information:

Lenalidomide 4'-PEG1-amine dihydrochloride

Lenalidomide 4'-PEG1-amine dihydrochloride is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide 4'-PEG1-amine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC .

Cat. No.: EX-A8999E    Purity: >98%
Chemical
Chemical structure of Lenalidomide 4'-PEG1-amine dihydrochloride


For research only, Do not use for Human!

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CAS No.2624336-86-1
Purity>98%
FormulaC17H24Cl2N4O4
Mol Weight419.303
ColorLight yellow to brown
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, sealed storage, away from moisture; In solvent -20°C, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Wang S, et al. Monofunctional intermediates for ligand-dependent target protein degradation. China, WO2017176958A1. 2017-10-12.

CoACoA of Lenalidomide 4'-PEG1-amine dihydrochloride
Smiles:O=C1NC(C(CC1)N2C(C3=C(C2)C(NCCOCCN)=CC=C3)=O)=O.Cl.Cl

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