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Product Information:

LEI105

LEI105 is a potent, highly selective, and reversible dual DAGL-α/DAGL-β inhibitor. Diacylglycerol lipase (DAGL)-α and -β are enzymes responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG).

Cat. No.: EX-A5179    Purity: >98%
Chemical
Chemical structure of LEI105


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg785Inquire
10mg1285Inquire
50mg2685Inquire


CAS No.1800327-36-9
Purity>98%
FormulaC25H24N2O2
Mol Weight384.4703
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  1: Baggelaar MP, et al. Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons. J Am Chem Soc. 2015 Jul 15;137(27):8851-7. doi: 10.1021/jacs.5b04883. Epub 2015 Jul 1. PubMed PMID: 26083464; PubMed Central PMCID: PMC4773911.
CoACoA of LEI105

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