LB244

LB244 is a homologue of BB-Cl-amidine, which is an orally effective STING inhibitor (EC50=0.8 μM) and can be used to inhibit STING-dependent inflammatory diseases. The pharmacokinetic properties of LB244 indicate limited oral activity in mice[1].


Cat. No.: EX-A16627	Purity: >98%

	Chemical structure of LB244

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
25mg	get quote

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CAS No.	3074622-05-9
Purity	>98%
Formula	C30H27N5O5
Mol Weight	537.5659
Color	White to light yellow
State	solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Barasa L, et al. Development of LB244, an Irreversible STING Antagonist. J Am Chem Soc. 2023 Sep 20;145(37):20273-20288..
CoA	CoA of LB244

Smiles:	C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)N[C@@H](CCCCNC(=O)C3=CC=C(O3)[N+](=O)[O-])C4=NC5=CC=CC=C5N4


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