LASSBio-873

LASSBio-873 is an orally active muscarinic cholinergic receptor (mAChR) agonist that crosses the blood-brain barrier. LASSBio-873 has potent analgesic effects on acute and inflammatory pain. The analgesic effect of LASSBio-873 can be inhibited by intrathecal injection of the M2 receptor antagonist methoctramine .


Cat. No.: EX-A9891	Purity: >98%

	Chemical structure of LASSBio-873

For research only, Do not use for Human!

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CAS No.	873694-54-3
Purity	>98%
Formula	C21H13N5O4
Mol Weight	399.359
Color	Yellow to orange
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20°C, 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Mendes TC, et al. Antihyperalgesic effects of a novel muscarinic agonist (LASSBio-873) in spinal nerve ligation in rats. Clin Exp Pharmacol Physiol. 2013 Jul;40(7):404-11.
CoA	CoA of LASSBio-873

Smiles:	O=C1N(C2=CC=C([N+]([O-])=O)C=C2)C(C3=C4C(N(C5=CC=CC=C5)N=C4C)=NC=C31)=O


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