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Product Information:

Larotinib

Larotinib is a potent broad-spectrum and orally active tyrosine kinase inhibitor (TKI) with EGFR as the main target with an IC50 of 0.6 nM.

Cat. No.: EX-A7708    Purity: >98%
Chemical
Chemical structure of Larotinib


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
10mg380In-stock
25mg685In-stock
50mg985In-stock
100mg1385In-stock
200mg1885In-stock
1g3385In-stock


CAS No.1438072-11-7
Purity>98%
FormulaC24H26ClFN4O4
Mol Weight488.939
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 125 mg/mL
Shelf Life>2 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent   -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Liu J, et al. Phase I Trial to Evaluate the Tolerance, Pharmacokinetics and Efficacy of the Broad-Spectrum ErbB Family Inhibitor Larotinib Mesylate in Patients With Advanced Solid Tumors. Front Pharmacol. 2021 Feb 18;12:636324.

CoACoA of Larotinib

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