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L2H2-6OTD intermediate-1

L2H2-6OTD intermediate-1 is an intermediate for the synthesis of L2H2-6OTD and can be used for ADC preparation. L2H2-6OTD, a telomestatin analog with telomerase inhibitory activity (IC50: 15 nM). For research use only. We do not sell to patients.

Cat. No.: EX-A17063    Purity: >98%
Chemical
Chemical structure of L2H2-6OTD intermediate-1


For research only, Do not use for Human!

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CAS No.912656-47-4
Purity>98%
FormulaC24H32N4O7S
Mol Weight520.598
ColorLight yellow to yellow
StateSolid
Shelf Life>3 years if stored properly
StoragePowder -20°C 3 years, 4°C 2 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Doi Takayuki, et al. Total Synthesis of (R)-Telomestatin. Organic Letters (2006), 8(18), 4165-4167.

[2]. Kazuaki Shibata, et al. Synthesis of Heptaoxazole Macrocyclic Analogues of Telomestatin. Chem. Soc. Jpn. Vol. 86, No. 12, 1453­1465

CoACoA of L2H2-6OTD intermediate-1
Smiles:CC1=C(C2=NC(C3=NC(C(OC)=O)=CO3)=C(O2)C)N=C(O1)[C@H](CSC(C)(C)C)NC(OC(C)(C)C)=O

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