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Product Information:

L-NIL hydrochloride

L-NIL hydrochloride is an inducible NO synthase inhibitor, with an IC50 of 3.3 μM for miNOS.

Cat. No.: EX-A6935    Purity: >98%
Chemical
Chemical structure of L-NIL hydrochloride


For research only, Do not use for Human!

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CAS No.150403-89-7
Purity>98%
FormulaC8H18ClN3O2
Mol Weight223.7
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Consuelo Pasten, et al. l-NIL prevents the ischemia and reperfusion injury involving TLR-4, GST, clusterin, and NFAT-5 in mice. Am J Physiol Renal Physiol. 2019 Apr 1;316(4):F624-F634.

[2]. Sharon Angela Tanuseputero, et al. Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis. Mediators Inflamm. 2020 May 11;2020:3201635.

[3]. Moore WM, et al. L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J Med Chem. 1994 Nov 11;37(23):3886-8.

CoACoA of L-NIL hydrochloride

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