background


Product Information:

L-NIL dihydrochloride

L-NIL dihydrochloride is an inducible NO synthase inhibitor, with an IC50 of 3.3 μM for miNOS.

Cat. No.: EX-A10387B    Purity: >98%
Chemical
Chemical structure of L-NIL dihydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
1gget quoteInquire


CAS No.159190-45-1
Purity>98%
FormulaC8H19Cl2N3O2
Mol Weight260.161
ColorWhite to off-white
StateSolid
SolubilitySoluble in DMSO/H2O
Shelf Life>3 years if stored properly
StoragePowder -20°C, sealed storage, away from moisture; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Consuelo Pasten, et al. l-NIL prevents the ischemia and reperfusion injury involving TLR-4, GST, clusterin, and NFAT-5 in mice. Am J Physiol Renal Physiol. 2019 Apr 1;316(4):F624-F634.

[2]. Sharon Angela Tanuseputero, et al. Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis. Mediators Inflamm. 2020 May 11;2020:3201635.

[3]. W M Moore, et al. L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J Med Chem. 1994 Nov 11;37(23):3886-8.

CoACoA of L-NIL dihydrochloride
Smiles:N[C@@H](CCCCNC(C)=N)C(O)=O.[H]Cl.[H]Cl

KEYWORDS: buy L-NIL dihydrochloride | L-NIL dihydrochloride supplier | purchase | cost | manufacturer | order | distributor | buy 159190-45-1 | 159190-45-1 supplier