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Product Information:

L-Cys-MMAE

L-Cys-MMAE (Cys-MC-VC-PAB-MMAE) is an ADC metabolite used in the synthesis of antibody-drug conjugates (ADCs).

Cat. No.: EX-A9874    Purity: >98%
Chemical
Chemical structure of L-Cys-MMAE


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg1685In-stock
10mg2585In-stock
25mg3785In-stock
100mg9685In-stock
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SynonymsCysteine-vc-mmae
Synonyms 2Cys-MC-VC-PAB-MMAE
CAS No.3051855-32-1
Purity>98%
FormulaC71H112N12O17S
Mol Weight1437.784
ColorWhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 1 year; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Krzyscik, Mateusz A et al. “Fibroblast Growth Factor 2 Conjugated with Monomethyl Auristatin E Inhibits Tumor Growth in a Mouse Model.” Biomacromolecules vol. 22,10 (2021): 4169-4180. doi:10.1021/acs.biomac.1c00662

CoACoA of L-Cys-MMAE
Smiles:[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN4C(=O)C(SC[C@@H](C(O)=O)N)CC4=O)=O)[C@H](C)C)=O)CCCNC(N)=O)=O)C=C3)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O

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