KX2-361

KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell.


Cat. No.: EX-A12330	Purity: >98%

	Chemical structure of KX2-361

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	420	In-stock
50mg	670	In-stock
100mg	1075	In-stock
250mg	2150	In-stock
500mg	3440	In-stock
1g	5500	In-stock

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CAS No.	897016-26-1
Purity	>98%
Formula	C24H24FN3O2
Mol Weight	405.4647
Color	White to off-white
State	Solid
Solubility	DMSO : 10.71 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Ciesielski MJ, et al. KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma. J Neurooncol. 2018 Dec;140(3):519-527.
CoA	CoA of KX2-361

Smiles:	O=C(NCC=1C=CC=C(F)C1)CC=2N=CC(=CC2)C3=CC=C(C=C3)N4CCOCC4


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