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Product Information:

KT185

KT185 is an orally-bioavailable, brain-penetrant and selective ABHD6 inhibitor, with an IC50 0.21 nM in Neuro2A cells .

Cat. No.: EX-A16709    Purity: >98%
Chemical
Chemical structure of KT185


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg872Inquire
100mg1456Inquire


CAS No.1472640-86-0
Purity>98%
FormulaC32H33N5O2
Mol Weight519.6367
Colorwhite to off-white
Statesolid
SolubilityDMSO : 30 mg/mL (57.73 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Shelf Life>3 years if stored properly
StoragePowder -20°C 3 years 4°C 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6). J Med Chem. 2013 Nov 14;56(21):8270-9.

CoACoA of KT185
Smiles:O=C(N1N=NC(C2=CC=C(C=C2)C3=CC=CC(C(N4CCCCC4)=O)=C3)=C1)N5C(CCCC5)C6=CC=CC=C6

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