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Product Information:

KT-474

KT-474 (KYM-001; Compound I-417) is an orally active PROTAC IRAK4 degrader with antitumor activities.

Cat. No.: EX-A8217    Purity: >98%
Chemical
Chemical structure of KT-474


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg1000In-stock
250mg1788In-stock
500mg2760In-stock
1g4480In-stock


SynonymsSAR444656
Synonyms 2KYM-001
CAS No.2432994-31-3
Purity>98%
FormulaC44H49F2N11O6
Mol Weight865.9268
Coloroff-white to yellow
Statesolid powder
SolubilityDMSO : 100 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. Patent WO2020113233A1.

CoACoA of KT-474
Smiles:O=C1N(C(CCC2=O)C(N2)=O)C3=CC=CC(C#CCOC(CC4)CCN4C[C@H]5CC[C@@](N(N=C6C(F)F)C=C6NC(C7=C(N=C(N8[C@@H](CO9)C[C@@H]9C8)C=C%10)N%10N=C7)=O)([H])CC5)=C3N1C

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