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Product Information:

KRAS inhibitor Compound 16h

Compound 16h is characterized as a highly potent multi-mutant KRAS inhibitor:

Cat. No.: EX-A16711    Purity: >98%
Chemical
Chemical structure of KRAS inhibitor Compound 16h


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg1950In-stock
10mg2850Inquire


Synonymstetracyclic quinazolines as multi-KRAS inhibitor
CAS No.3033637-82-7
Purity>98%
FormulaC29H28ClF3N6O3S
Mol Weight633.084
 
 
Reference:  

[1]. Hong C, et al. Discovery of novel tetracyclic quinazolines as multi-KRASáinhibitors for the treatment of solid tumors[J]. Bioorganic & Medicinal Chemistry Letters, 2025, 118: 130087.

CoACoA of KRAS inhibitor Compound 16h
Smiles:FC=1C=2C3=C(N4[C@](COC3=C(Cl)C1C5=C6C(=C(F)C=C5)SC(N)=N6)(COCCC4)[H])N=C(OC[C@@]78N(C[C@H](F)C7)CCC8)N2

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