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Product Information:

KRAS inhibitor-38

KRAS inhibitor-38 (Example 18) is a KRAS inhibitor that effectively suppresses the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.

Cat. No.: EX-A13370    Purity: >98%
Chemical
Chemical structure of KRAS inhibitor-38


For research only, Do not use for Human!

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CAS No.3059496-10-2
Purity>98%
FormulaC53H68ClF2N9O8S
Mol Weight1064.677
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Jianguo Chen, et al. Tricyclic compounds for the treatment of cancer. Patents, WO2024208934, 2024-10-10.

CoACoA of KRAS inhibitor-38
Smiles:CO[C@H](C1=[C@@](C=C(C=N1)N2CCOCC2)[C@@]3=C4CC(C)(COC([C@@H]5CCCN(C([C@H](CC6=NC(C7=CC4=C8C(CCCN83)=C7)=CS6)NC([C@@H](N(C(C9(CCN(CC9)C([C@@H](Cl)F)=O)F)=O)C)C(C)C)=O)=O)N5)=O)C)C

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