KNT-127

KNT-127 is a potent and selective δ-opioid receptor agonist effective by systemic administration. KNT-127 shows selectivity for the δ-receptor (Ki 0f 21.3, 0.16, 153 nM for opioid μ-, δ-, and κ-receptors, respectively).


Cat. No.: EX-A7846F	Purity: >98%

	Chemical structure of KNT-127

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	1585	In-stock
25mg	2985	In-stock
50mg	4885	In-stock
100mg	7862	In-stock

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CAS No.	1256921-89-7
Purity	>98%
Formula	C24H24N2O2
Mol Weight	372.4596
Color	Off-white to light yellow
State	solid powder
Solubility	DMSO : 25 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 year
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Nagase H, et al. Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration. Bioorg Med Chem Lett. 2010;20(21):6302-6305. [2]. Tanahashi S, et al. Novel δ1-receptor agonist KNT-127 increases the release of dopamine and L-glutamate in the striatum, nucleus accumbens and median pre-frontal cortex. Neuropharmacology. 2012;62(5-6):2057-2067.
CoA	CoA of KNT-127

Smiles:	O[C@@]12[C@]3(CC4=NC5=CC=CC=C5C=C4C2)C6=CC(O)=CC=C6C[C@H]1N(CC3)C


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