KG5

KG5 is an orally active dual PDGFRβ and B-Raf allosteric inhibitor. KG5 also inhibits Flt3, KIT and c-Raf. KG5 has anticancer, antiangiogenic activities.


Cat. No.: EX-A6811	Purity: >98%

	Chemical structure of KG5

For research only, Do not use for Human!

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Synonyms	KG 5
CAS No.	877874-85-6
Purity	>98%
Formula	C20H16F3N7OS
Mol Weight	459.448
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4°C, protect from light; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Eric A Murphy, et al. Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4299-304.
CoA	CoA of KG5


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