KAR-5417

Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.


Cat. No.: EX-A5965	Purity: >98%

	Chemical structure of KAR-5417

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	885	In-stock
10mg	1285	In-stock
25mg	2285	In-stock
50mg	3685	In-stock
100mg	5685	In-stock
500mg	get quote	In-stock

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Synonyms	Rodatristat
CAS No.	1673568-73-4
Purity	>98%
Formula	C27H27ClF3N5O3
Mol Weight	561.983
Color	White to off-white
State	solid powder
Solubility	Soluble in DMSO 20 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Goldberg DR, et al. Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg Med Chem Lett. 2017 Feb 1;27(3):413-419.
CoA	CoA of KAR-5417


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