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Product Information:

Kainic acid

Kainic acid is a potent excitotoxic agent. Kainic acid hydrate also is an agonist for a subtype of ionotropic glutamate receptor. Kainic acid induces seizures.

Cat. No.: EX-A8001    Purity: >98%
Chemical
Chemical structure of Kainic acid


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg900In-stock
250mg1765In-stock
500mgget quoteIn-stock
1gget quoteIn-stock


CAS No.487-79-6
Purity>98%
FormulaC10H15NO4
Mol Weight213.2304
Colorwhite to off-white
Statesolid powder
SolubilityDMSO : 40 mg/mL H2O : 10 mg/mL
Shelf Life>3 years if stored properly
StoragePowder 4℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cincioğlu-Palabiyik M, et al. Chronic levetiracetam decreases hippocampal and testicular aromatase expression in normal but not kainic acid-induced experimental model of acute seizures in rats. Neuroreport. 2017 Sep 27;28(14):903-909.

[2]. Wang Q, et al. Kainic acid-mediated excitotoxicity as a model for neurodegeneration. Mol Neurobiol. 2005;31(1-3):3-16.

[3]. Lévesque M, et al. The kainic acid model of temporal lobe epilepsy. Neurosci Biobehav Rev. 2013 Dec;37(10 Pt 2):2887-99.

[4]. Scherer-Singler U, McGeer EG. Distribution and persistence of kainic acid in brain. Life Sci. 1979 Mar 12;24(11):1015-22.

[5]. Zheng Z, et al. The effect of dipeptidyl peptidase IV on disease-associated microglia phenotypic transformation in epilepsy. J Neuroinflammation. 2021 May 11;18(1):112.

CoACoA of Kainic acid
Smiles:O=C(O)C[C@@H]1[C@@H](C(O)=O)NC[C@@H]1C(C)=C

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