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Product Information:

K22

K22 is an anti-Coronaviral compound. K22 reduces double-stranded RNA. K22 displays antiviral activity beyond the Coronavirinae subfamily, namely against nidoviruses of the Torovirinae subfamily (EToV and WBV) and members of the Arteriviridae family (PRRSV, EAV). K22 displays antiviral activity against HCoV-229E.

Cat. No.: EX-A14204    Purity: >98%
Chemical
Chemical structure of K22


For research only, Do not use for Human!

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CAS No.2141978-86-9
Purity>98%
FormulaC27H25BrN2O3
Mol Weight505.403
ColorWhite to off-white
StateSolid
SolubilityDMSO : 50 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20°C, 3 years; In solvent -20°C, 1 month.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Lundin A, et al. Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS Pathog. 2014;10(5):e1004166. Published 2014 May 29.

[2]. Rappe JCF, et al. Antiviral activity of K22 against members of the order Nidovirales. Virus Res. 2018;246:28-34.

CoACoA of K22
Smiles:C1CN(CCC1(C2=CC=C(C=C2)Br)O)C(=O)/C(=C/C3=CC=CC=C3)/NC(=O)C4=CC=CC=C4

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