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Product Information:

JX 401

JX401 is a potent inhibitor of p38alpha, containing a 4-benzylpiperidine motif. p38alpha is hyperactive in inflammatory diseases, and various indications suggest that its inhibition would reverse inflammation. JX401 has the potential for the research of inflammation.

Cat. No.: EX-A14190    Purity: >98%
Chemical
Chemical structure of JX 401


For research only, Do not use for Human!

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CAS No.349087-34-9
Purity>98%
FormulaC21H25NO2S
Mol Weight355.494
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Friedmann Y, et al. JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. Mol Pharmacol. 2006;70(4):1395-1405.

CoACoA of JX 401
Smiles:COC1=C(C=CC(=C1)SC)C(=O)N2CCC(CC2)CC3=CC=CC=C3

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